Physical form optimization

 

 

Early characterization of Discovery bulks often helps identifying critical milestones to be included into the drug candidate preclinical development plan. Drugabilis regularly performs those measurements on minute bulk amounts.

 Thanks to our well-equipped characterization platform, Drugabilis can work on:

  • Crystallinity assessment
  • Thermal profile assessment
  • Hygroscopicity measurement
  • Hot-stage microscopic observations
  • Hydrate and solvate identification
  • API physical form stability evaluation under stress conditions
  • Relative stability of polymorphs
  • Crystallization of amorphous API
  • Crystallization process support
  • Polymorph quantification